Combined Pituitary Hormone Deficiency

A hereditary autosomal recessive form of hypopituitarism that is characterized by growth retardation, HYPOTHYROIDISM, reduced levels of CORTISOL, and absent or DELAYED PUBERTY due to low levels of LUTEINIZING HORMONE or FOLLICLE-STIMULATING HORMONE . Rarely, INTELLECTUAL DISABILITY, neck abnormalities, and OPTIC NERVE defects may also occur. Mutations in the PROP1 gene have been identified in some cases. OMIM: 262600

Also Known As:

Panhypopituitarism

Nervous System Diseases: 14178
- Central Nervous System Diseases: 4213
  - Brain Diseases: 15694
    - Hypothalamic Diseases: 40
      - Pituitary Diseases: 562
        Hypopituitarism: 2246
        Combined Pituitary Hormone Deficiency: 590
Endocrine System Diseases: 968
- Pituitary Diseases: 562
  - Hypopituitarism: 2246
    - Combined Pituitary Hormone Deficiency: 590

M L Sobrier Selected Research

M L Sobrier Research Topics

Disease

Drug/Important Bio-Agent (IBA)